Different molecular patterns in glioblastoma multiforme subtypes upon recurrence
نویسندگان
چکیده
منابع مشابه
Glioblastoma Multiforme in Children, A Case-Report
ABSTRACT: Glioblastoma multiforme is the most malignant primary brain tumor .It usually occurs in the 5th and 6th decades of life and is rare in childern. In this paper a case of glioblastoma multiforme is reported in a ten year - old child who presented with two week's history of headache with no neurological defect.C.T scan revealed å right frontal mass with massive surrounding oedema. He w...
متن کاملCombined Salvage Therapies for Recurrent Glioblastoma Multiforme: Treatment Options in Multifocal and Multicentric Patterns of Recurrence
Despite the advancement made in the fields of neurosurgery, neuro-oncology, medical oncology, and radiation oncology, patients with recurrent high grade gliomas represent a unique challenge to the treating physicians [1,2]. Gliomas have the ability to disseminate along established CNS routes, such as white matter tracts, cerebrospinal fluid, or local invasion [3]. Multifocal appearance accordin...
متن کاملInitial metabolomic analysis of glioblastoma multiforme subtypes by HRMAS
D. Valverde-Saubí, A. P. Candiota, M. A. Molins, M. Feliz, Ó. Godino, J. Martino, J. J. Acebes, and C. Arús Bioquímica i Biologia molecular, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Barcelona, Spain, Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Cerdanyola del Vallès, Barcelona, Spain, Servei RMN Parc Científic de Barcelona...
متن کاملBiological and molecular analysis of a low-grade recurrence of a glioblastoma multiforme.
We and others have reported that human malignant gliomas demonstrate intratumor heterogeneity in which many regions may be benign; however, the presence of regions of increased malignancy in these same tumors is generally indicative of poor patient prognosis. These data suggested that tumor progression may be a local phenomenon, resulting in regions that progress to a more malignant type prior ...
متن کاملMultiple microsurgical resections for repeated recurrence of glioblastoma multiforme.
OBJECTIVES There has been little evidence so far supporting further surgical intervention in case of repeated recurrence of glioblastoma multiforme (GBM). Thus, the efficacy and utility of repeated resection remains unclear but worthy of consideration. The aim of this study was to review the efficacy of multiple repeated resections in patients with recurrent GBM. METHODS Forty-two patients un...
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ژورنال
عنوان ژورنال: Journal of Neuro-Oncology
سال: 2009
ISSN: 0167-594X,1573-7373
DOI: 10.1007/s11060-009-9967-4